A house fire takes the life of a 17-year-old. Investigators quickly discover it was intentionally set, but it would take years before they learned anything more.

One is found dead, and the other is missing. Police would need to untangle their lives before uncovering the truth about what happened to them both.

In this special re-release of the very first Anatomy of Murder episode, Scott and Anna return to the story that started it all—the 1970 murder of Loretta Jones. When her daughter Heidi grew up, she refused to let the case fade away, leading to a shocking confession nearly half a century later.

A mass murder strikes at the heart of a community when the employees of its local paper are the targets. The preplanning and reasoning propelling the horrific attack is mind-boggling.

When a healthy mom becomes suddenly ill and dies, doctors and family are baffled. Foul play is soon suspected, but the biggest question would be, could they prove it?

A woman claims she had a dream that she hurt someone. After a body is found, investigators needed to uncover: was this ‘dream’ a figment of imagination or a confession?

A young woman is shot and killed at work, in a local home improvement store. The shooter’s unlikely accomplice would prove pivotal to this crime.

Two prosecutors are gunned down within a short span. A tip comes in that there will be more bloodshed. The entire justice system was on edge in a case striking at its heart. Can police stop this murderer before he strikes again?

Two young teens are found dead in their home. One family is desperate for answers. Another has to confront an unthinkable truth.

911 is called to report a woman is found unresponsive in her bathtub. Accident or murder? Her family suspects foul play and will not give up until they receive justice.

A woman disappears as she navigates a recent divorce. Did she willingly disappear, or was it foul play? And if so, by whom? It would be money and checks that helped solve the mystery.

A woman knocks on the door, and within minutes, the man she asked for is outside dead. His family wanted answers. Detectives put the pieces together one by one to figure out this complex case.

A man’s body is found in the park. What happened would first center on a car. The end would involve murder.

A young man is found murdered in his home. Several hours later, a woman is found dead only blocks away. Coincidence or the work of one killer? Coins would help investigators find the answer.

A bomb explodes in a day spa, destroying the building, killing its owner, and seriously injuring others. Would the blast be the work of a terrorist act or something else? Unraveling the mystery became a puzzle that was solved one piece at a time

In a small Indiana town, investigators connect the dots in the murders of young women. But sometimes, shocking coincidences are nothing more than that.

A young college student is murdered, sending shockwaves through the community. But another murder, eerily similar, makes investigators question if a serial killer is loose in this college community.

A murder spree leaves 5 dead—once the killer was identified, would the motive be revealed? What he said shocked everyone.

A man on a first date is soon found dead in the street. The story behind the who and why will be baffling and up the enormity of the tragedy.

This part 2 is the dramatic conclusion to a case that took two lives and almost 3. It broke all family boundaries. A prosecutor was left to unravel the pieces.