Though the daughter of a Roman senator and a great beauty, she fled the world and entered a monastery in Mesopotamia. (So great was her beauty that the abbess had her stand behind a screen while reading to her monastic sisters.) At that time the Emperor Diocletian sent a certain Selenus, along with his nephew Lysimachus, on a mission to find and destroy Christians in the East. Though Selenus was a fierce persecutor of the Christians, Lysimachus felt sympathy for them and secretly protected them whenever he could. Selenus and his party came to Nisibis, where Febronia's virtue and holiness had already become well-known, though she was still only twenty years old. Selenus summoned her and made every effort to convince her to renounce her faith. When she stood firm, she was first viciously dismembered then beheaded. Lysimachus gathered her relics and took them to the monastery for burial. At the monastery he, together with many soldiers, were baptized. The holy Febronia's relics worked many healings, and she herself appeared to the other nuns on the anniversary of her repose, standing in her usual place among her sisters. Her relics were translated to Constantinople in 363.