Shedeur Sanders prepares for his second consecutive start as the San Francisco 49ers visit the Cleveland Browns with inclement weather in the forecast. Spencer German and Eric Crocker break down the biggest storylines, from Sanders starting again, to 49ers QB Brock Purdy looking to bounce back from a rough return on Monday Night Football. The guys also breakdown the key matchups, Myles Garrett vs. Trent Williams, Carson Schwesinger vs. Christian McCaffrey and more. Can the Browns' elite defense tip the scales in Cleveland's favor, or will San Francisco’s offensive weapons prove too much? San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker. Follow & Subscribe on all Podcast platforms…🎧 https://link.chtbl.com/LO49ers?sid=YouTube Locked On NFL League-Wide: Every Team, Fantasy, Draft & More🎧 https://linktr.ee/LockedOnNFL Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans.Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker Support Us By Supporting Our Sponsors! PelotonLet yourself run, lift, flex, and push forward. Explore the new Peloton Cross Training Tread+ today at https://www.onepeloton.com. PrizePicksDownload the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup.Click Here: https://prizepicks.onelink.me/LME0/LOCKEDONNFL GametimeDownload the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime. FanDuelRight now, new customers can bet just FIVE dollars and if your bet wins—you’ll get THREE HUNDRED dollars in bonus bets to use across the app. FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.