Free RPE/RIR guide: https://data-drivenstrength.ck.page/rpe-guide Greg Nuckols: https://www.strongerbyscience.com https://www.strongerbyscience.com/effective-reps/ https://www.instagram.com/gregnuckols/?hl=en 0:00:00 Intro 0:04:50 Overview of New Proximity to Failure Meta-Regression 0:17:00 Common Misinterpretations of the Results 0:20:00 The Resurgence of the Effective Reps Model 0:40:00 The Desire for a Proxy Metric of Hypertrophy 1:18:00 The Mechanistic Rationale of Effective Reps 1:50:00 Other Factors Influencing Muscle Growth 2:09:00 Metabolic Stress as a Mediator 3:05:00 Is Force on the Fiber Level High at the End of a Set? 3:40:00 Practical Applications Papers Mentioned: https://sportrxiv.org/index.php/server/preprint/view/295 https://pubmed.ncbi.nlm.nih.gov/30335577/ https://www.strongerbyscience.com/research-spotlight-cardio-bigger/ https://pubmed.ncbi.nlm.nih.gov/37382939/ https://link.springer.com/article/10.1007/s11332-022-00907-2 https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005581 https://www.sciencedirect.com/science/article/pii/S1050641123000330 https://journals.lww.com/nsca-jscr/Fulltext/2020/11000/Neural_Drive_is_Greater_for_a_High_Intensity.1.aspx?context=FeaturedArticles&collectionId=1 https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.13675 https://www.sciencedirect.com/science/article/pii/S105064112300069X https://pubmed.ncbi.nlm.nih.gov/11102845/ https://www.researchgate.net/publication/354976236_Neuromuscular_responses_to_isometric_concentric_and_eccentric_contractions_of_the_knee_extensors_at_the_same_torque-time_integral https://pubmed.ncbi.nlm.nih.gov/16282433/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473942/ DDS Training Takeaway Newsletter: https://www.data-drivenstrength.com/newsletter DDS 1:1 Coaching:  http://data-drivenstrength.ck.page/info Infinity Programs System: https://www.data-drivenstrength.com/infinity Follow Zac on Instagram: https://www.instagram.com/zac.datadrivenstrength/?hl=en Follow Josh on Instagram: https://www.instagram.com/josh.datadrivenstrength/?hl=en Music by Joystock - https://www.joystock.com