This lecture discusses key ideas John Searle's article "Minds, Brains, & Programs", first published in The Behavioral And Brain Sciences In 1980, considered to be an important contribution to theorizing about the possibility and nature of artificial intelligence, not least by introducing his famous "Chinese Room" thought experiment. Specifically it examines his response to one of the replies made by proponents of strong AI claims, which he calls the "systems reply', and which he considers to be rather implausible. To support my ongoing work, go to my Patreon site - www.patreon.com/sadler If you'd like to make a direct contribution, you can do so here - www.paypal.me/ReasonIO - or at BuyMeACoffee - www.buymeacoffee.com/A4quYdWoM You can find over 4500 philosophy videos in my main YouTube channel - www.youtube.com/user/gbisadler Get John Searle, Minds, Brains, & Programs here - https://home.csulb.edu/~cwallis/382/readings/482/searle.minds.brains.programs.bbs.1980.pdf