Buffalo Bills aim to defend their AFC East dominance as they face a surging New England Patriots squad with everything on the line. Can Josh Allen lead the Bills past Drake May and a re-energized Patriots team determined to prove their Week 5 victory was no fluke? Nick Cattles and Joe Marino break down the pivotal storylines, including playoff implications, red zone efficiency, and whether Mike Vrabel’s hard-hitting messaging will rally New England in Foxborough.Key matchups take center stage as the hosts spotlight the Bills’ rushing attack versus the Patriots’ struggling run defense, the chess match between Christian Barmore and Buffalo’s offensive line, and how each defense handles third-down pressure. Plus, they discuss the evolution of Drake Maye’s MVP campaign, critical injuries on both sides, and what each team must do to secure the division crown. Don’t miss this energetic, insight-packed preview of a season-defining AFC East showdown.Visit https://www.thejoemarino.com/ for details on Substack, Subtext, Merch and more! Follow & Subscribe on all Podcast platforms… 🎧 https://link.chtbl.com/LOBills?sid=Yo...Locked On NFL League-Wide: Every Team, Fantasy, Draft & More🎧 https://linktr.ee/LockedOnNFLEverydayer Club  If you never miss an episode, it’s time to make it official. Join the Locked On Everydayer Club and get ad-free audio, access to our members-only Discord, and more — all built for our most loyal fans. Click here to learn more and join your team’s community: https://lockedonpodcasts.com/everydayerclub  Support Us By Supporting Our Sponsors!Aura FramesFor a limited time, save on the perfect gift by visiting https://AuraFrames.com to get $35 off Aura’s best-selling Carver Mat frames - named #1 by Wirecutter - by using promo code LOCKEDON at checkout.FanDuelIf you want to be right in the middle of the action this season, visit FanDuel.com and place your NFL live bets all season long.PrizePicksDownload the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup.Click Here: https://prizepicks.onelink.me/LME0/LOCKEDONNFLGametimeDownload the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime.Mint MobileTurn your expensive wireless present into a huge wireless savings future by switching to Mint. Shop Mint Unlimited Plans at http://MINTMOBILE.com/LOCKEDONNFL. Disclaimer: Limited time offer. Upfront payment of:  $45 for 3-mo., $90 for 6-mo., or $180 for 12-mo. plan required ($15/mo. equivalent). Taxes & fees Initial plan term only. Greater than 35GB may slow when network is busy. Capable device required. Availability, speed, & coverage vari